diff --git a/extensions/cornerstone/src/getHangingProtocolModule.ts b/extensions/cornerstone/src/getHangingProtocolModule.ts
index 6a1fc8a1c0a..d04024f2eb1 100644
--- a/extensions/cornerstone/src/getHangingProtocolModule.ts
+++ b/extensions/cornerstone/src/getHangingProtocolModule.ts
@@ -6,6 +6,7 @@ import { only3D } from './hps/only3D';
 import { primary3D } from './hps/primary3D';
 import { primaryAxial } from './hps/primaryAxial';
 import { frameView } from './hps/frameView';
+import { mgCC, mgMLO } from './hps/mammo';
 
 function getHangingProtocolModule() {
   return [
@@ -41,6 +42,14 @@ function getHangingProtocolModule() {
       name: frameView.id,
       protocol: frameView,
     },
+    {
+      name: mgCC.id,
+      protocol: mgCC,
+    },
+    {
+      name: mgMLO.id,
+      protocol: mgMLO,
+    },
   ];
 }
 
diff --git a/extensions/cornerstone/src/hps/mammo.ts b/extensions/cornerstone/src/hps/mammo.ts
new file mode 100644
index 00000000000..b2b140a80fe
--- /dev/null
+++ b/extensions/cornerstone/src/hps/mammo.ts
@@ -0,0 +1,57 @@
+export const mgCC = {
+  id: 'mgCC',
+  name: 'mammo-cc',
+  imageLoadStrategy: 'interleaveTopToBottom',
+  protocolMatchingRules: [
+    { attribute: 'ModalitiesInStudy', constraint: { contains: ['MG', 'DX'] } },
+  ],
+  displaySetSelectors: {
+    isRCC: {
+      seriesMatchingRules: [
+        { weight: 1, attribute: 'isRCC', constraint: { equals: { value: true } } },
+      ],
+    },
+    isLCC: {
+      seriesMatchingRules: [
+        { weight: 1, attribute: 'isLCC', constraint: { equals: { value: true } } },
+      ],
+    },
+  },
+  stages: [
+    {
+      name: 'default',
+      viewportStructure: { layoutType: 'grid', properties: { rows: 1, columns: 2 } },
+      viewports: [{ displaySets: [{ id: 'isRCC' }] }, { displaySets: [{ id: 'isLCC' }] }],
+    },
+  ],
+  numberOfPriorsReferenced: -1,
+};
+
+export const mgMLO = {
+  id: 'mgMLO',
+  name: 'mammo-mlo',
+  imageLoadStrategy: 'interleaveTopToBottom',
+  protocolMatchingRules: [
+    { attribute: 'ModalitiesInStudy', constraint: { contains: ['MG', 'DX'] } },
+  ],
+  displaySetSelectors: {
+    isRMLO: {
+      seriesMatchingRules: [
+        { weight: 1, attribute: 'isRMLO', constraint: { equals: { value: true } } },
+      ],
+    },
+    isLMLO: {
+      seriesMatchingRules: [
+        { weight: 1, attribute: 'isLMLO', constraint: { equals: { value: true } } },
+      ],
+    },
+  },
+  stages: [
+    {
+      name: 'default',
+      viewportStructure: { layoutType: 'grid', properties: { rows: 1, columns: 2 } },
+      viewports: [{ displaySets: [{ id: 'isRMLO' }] }, { displaySets: [{ id: 'isLMLO' }] }],
+    },
+  ],
+  numberOfPriorsReferenced: -1,
+};
diff --git a/platform/core/src/services/HangingProtocolService/HangingProtocolService.ts b/platform/core/src/services/HangingProtocolService/HangingProtocolService.ts
index 929f31100cb..0118b0d71f3 100644
--- a/platform/core/src/services/HangingProtocolService/HangingProtocolService.ts
+++ b/platform/core/src/services/HangingProtocolService/HangingProtocolService.ts
@@ -10,6 +10,7 @@ import * as HangingProtocol from '../../types/HangingProtocol';
 import { isDisplaySetFromUrl, sopInstanceLocation } from './custom-attribute/isDisplaySetFromUrl';
 import numberOfDisplaySetsWithImages from './custom-attribute/numberOfDisplaySetsWithImages';
 import seriesDescriptionsFromDisplaySets from './custom-attribute/seriesDescriptionsFromDisplaySets';
+import isMammoPos from './custom-attribute/isMammoPos';
 import uuidv4 from '../../utils/uuidv4';
 
 type Protocol = HangingProtocol.Protocol | HangingProtocol.ProtocolGenerator;
@@ -110,6 +111,22 @@ export default class HangingProtocolService extends PubSubService {
       description: 'Number of displays sets with images',
       callback: numberOfDisplaySetsWithImages,
     },
+    isRCC: {
+      name: 'is rcc',
+      callback: displaySet => isMammoPos(displaySet, 'R', 'CC'),
+    },
+    isLCC: {
+      name: 'is lcc',
+      callback: displaySet => isMammoPos(displaySet, 'L', 'CC'),
+    },
+    isRMLO: {
+      name: 'is rmlo',
+      callback: displaySet => isMammoPos(displaySet, 'R', 'MLO'),
+    },
+    isLMLO: {
+      name: 'is lmlo',
+      callback: displaySet => isMammoPos(displaySet, 'L', 'MLO'),
+    },
   };
   listeners = {};
   registeredImageLoadStrategies = {};
diff --git a/platform/core/src/services/HangingProtocolService/custom-attribute/isMammoPos.ts b/platform/core/src/services/HangingProtocolService/custom-attribute/isMammoPos.ts
new file mode 100644
index 00000000000..7f6de2687d1
--- /dev/null
+++ b/platform/core/src/services/HangingProtocolService/custom-attribute/isMammoPos.ts
@@ -0,0 +1,15 @@
+export default function isMammoPos(displaySet: any, pos: 'R' | 'L', type: 'CC' | 'MLO') {
+  const instanceTags = displaySet.instances[0];
+  const viewCode = instanceTags.ViewCodeSequence?.[0]?.CodeValue;
+  const laterality =
+    instanceTags.ImageLaterality ||
+    instanceTags.Laterality ||
+    instanceTags.SharedFunctionalGroupsSequence?.[0]?.FrameAnatomySequence?.[0]?.FrameLaterality;
+
+  const typeToCodeMap = {
+    CC: 'R-10242',
+    MLO: 'R-10226',
+  };
+
+  return laterality === pos && viewCode === typeToCodeMap[type];
+}