diff --git a/dotnet/src/Functions/Functions.OpenApi/RestApiOperationRunner.cs b/dotnet/src/Functions/Functions.OpenApi/RestApiOperationRunner.cs
index 9c1c2bcb1177..3c1038c12dd8 100644
--- a/dotnet/src/Functions/Functions.OpenApi/RestApiOperationRunner.cs
+++ b/dotnet/src/Functions/Functions.OpenApi/RestApiOperationRunner.cs
@@ -350,7 +350,10 @@ private async Task<RestApiOperationResponse> ReadContentAndCreateOperationRespon
             mediaType = mediaTypeFallback;
         }
 
-        if (!this._payloadFactoryByMediaType.TryGetValue(mediaType!, out var payloadFactory))
+        // Remove media type parameters, such as x-api-version, from the "text/plain; x-api-version=2.0" media type string.
+        mediaType = mediaType!.Split(';').First();
+
+        if (!this._payloadFactoryByMediaType.TryGetValue(mediaType, out var payloadFactory))
         {
             throw new KernelException($"The media type {mediaType} of the {operation.Id} operation is not supported by {nameof(RestApiOperationRunner)}.");
         }
diff --git a/dotnet/src/Functions/Functions.UnitTests/OpenApi/OpenApiKernelPluginFactoryTests.cs b/dotnet/src/Functions/Functions.UnitTests/OpenApi/OpenApiKernelPluginFactoryTests.cs
index 2242f5032610..eb223323b86c 100644
--- a/dotnet/src/Functions/Functions.UnitTests/OpenApi/OpenApiKernelPluginFactoryTests.cs
+++ b/dotnet/src/Functions/Functions.UnitTests/OpenApi/OpenApiKernelPluginFactoryTests.cs
@@ -8,6 +8,7 @@
 using System.Net.Http;
 using System.Net.Mime;
 using System.Text;
+using System.Text.Json.Nodes;
 using System.Threading.Tasks;
 using Microsoft.SemanticKernel;
 using Microsoft.SemanticKernel.Plugins.OpenApi;
@@ -517,6 +518,41 @@ public void ItCreatesPluginFromOpenApiSpecificationModel()
         Assert.Same(operations[0], function.Metadata.AdditionalProperties["operation"]);
     }
 
+    [Fact]
+    public async Task ItShouldWorkWithPayloadMediaTypesDeclaredWithParametersAsync()
+    {
+        // Arrange
+        using var messageHandlerStub = new HttpMessageHandlerStub();
+        using var httpClient = new HttpClient(messageHandlerStub, false);
+
+        this._executionParameters.EnableDynamicPayload = true;
+        this._executionParameters.HttpClient = httpClient;
+
+        var arguments = new KernelArguments
+        {
+            ["scenario"] = "fake-scenario",
+        };
+
+        var kernel = new Kernel();
+
+        var openApiDocument = ResourcePluginsProvider.LoadFromResource("documentV3_0.json");
+
+        var plugin = await OpenApiKernelPluginFactory.CreateFromOpenApiAsync("fakePlugin", openApiDocument, this._executionParameters);
+
+        // Act
+        // The media type string for the joke operation is declared with the x-api-version parameter: "application/json; x-api-version=2.0."
+        var result = await kernel.InvokeAsync(plugin["Joke"], arguments);
+
+        // Assert
+        var messageContent = messageHandlerStub.RequestContent;
+        Assert.NotNull(messageContent);
+
+        var deserializedPayload = await JsonNode.ParseAsync(new MemoryStream(messageContent));
+        Assert.NotNull(deserializedPayload);
+
+        Assert.Equal("fake-scenario", deserializedPayload["scenario"]!.GetValue<string>());
+    }
+
     /// <summary>
     /// Generate theory data for ItAddSecurityMetadataToOperationAsync
     /// </summary>