diff --git a/newrelic/config.py b/newrelic/config.py
index b4368fe70..9896d6a5e 100644
--- a/newrelic/config.py
+++ b/newrelic/config.py
@@ -3166,6 +3166,9 @@ def _process_module_builtin_defaults():
     _process_module_definition("MySQLdb", "newrelic.hooks.database_mysqldb", "instrument_mysqldb")
     _process_module_definition("pymysql", "newrelic.hooks.database_pymysql", "instrument_pymysql")
 
+    _process_module_definition("aiomysql", "newrelic.hooks.database_aiomysql", "instrument_aiomysql")
+    _process_module_definition("aiomysql.pool", "newrelic.hooks.database_aiomysql", "instrument_aiomysql_pool")
+
     _process_module_definition("pyodbc", "newrelic.hooks.database_pyodbc", "instrument_pyodbc")
 
     _process_module_definition("pymssql", "newrelic.hooks.database_pymssql", "instrument_pymssql")
diff --git a/newrelic/hooks/database_aiomysql.py b/newrelic/hooks/database_aiomysql.py
new file mode 100644
index 000000000..847c961d8
--- /dev/null
+++ b/newrelic/hooks/database_aiomysql.py
@@ -0,0 +1,106 @@
+# Copyright 2010 New Relic, Inc.
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#      http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+import sys
+
+from newrelic.api.database_trace import register_database_client
+from newrelic.api.function_trace import FunctionTrace
+from newrelic.common.object_names import callable_name
+from newrelic.common.object_wrapper import (
+    ObjectProxy,
+    wrap_function_wrapper,
+    wrap_object,
+)
+from newrelic.hooks.database_dbapi2_async import (
+    AsyncConnectionFactory as DBAPI2AsyncConnectionFactory,
+)
+from newrelic.hooks.database_dbapi2_async import (
+    AsyncConnectionWrapper as DBAPI2AsyncConnectionWrapper,
+)
+from newrelic.hooks.database_dbapi2_async import (
+    AsyncCursorWrapper as DBAPI2AsyncCursorWrapper,
+)
+
+
+class AsyncCursorContextManagerWrapper(ObjectProxy):
+
+    __cursor_wrapper__ = DBAPI2AsyncCursorWrapper
+
+    def __init__(self, context_manager, dbapi2_module, connect_params, cursor_args):
+        super().__init__(context_manager)
+        self._nr_dbapi2_module = dbapi2_module
+        self._nr_connect_params = connect_params
+        self._nr_cursor_args = cursor_args
+
+    async def __aenter__(self):
+        cursor = await self.__wrapped__.__aenter__()
+        return self.__cursor_wrapper__(cursor, self._nr_dbapi2_module, self._nr_connect_params, self._nr_cursor_args)
+
+    async def __aexit__(self, exc, val, tb):
+        return await self.__wrapped__.__aexit__(exc, val, tb)
+
+
+class AsyncConnectionWrapper(DBAPI2AsyncConnectionWrapper):
+
+    __cursor_wrapper__ = AsyncCursorContextManagerWrapper
+
+
+class AsyncConnectionFactory(DBAPI2AsyncConnectionFactory):
+
+    __connection_wrapper__ = AsyncConnectionWrapper
+
+
+def wrap_pool__acquire(dbapi2_module):
+    async def _wrap_pool__acquire(wrapped, instance, args, kwargs):
+        rollup = ["Datastore/all", f"Datastore/{dbapi2_module._nr_database_product}/all"]
+
+        with FunctionTrace(name=callable_name(wrapped), terminal=True, rollup=rollup, source=wrapped):
+            connection = await wrapped(*args, **kwargs)
+            connection_kwargs = getattr(instance, "_conn_kwargs", {})
+            return AsyncConnectionWrapper(connection, dbapi2_module, (((), connection_kwargs)))
+
+    return _wrap_pool__acquire
+
+
+def instance_info(args, kwargs):
+    def _bind_params(host=None, user=None, password=None, db=None, port=None, *args, **kwargs):
+        return host, port, db
+
+    host, port, db = _bind_params(*args, **kwargs)
+
+    return (host, port, db)
+
+
+def instrument_aiomysql(module):
+    register_database_client(
+        module,
+        database_product="MySQL",
+        quoting_style="single+double",
+        explain_query="explain",
+        explain_stmts=("select",),
+        instance_info=instance_info,
+    )
+
+    # Only instrument the connect method directly, don't instrument
+    # Connection. This follows the DBAPI2 spec and what was done for
+    # PyMySQL which this library is based on.
+
+    wrap_object(module, "connect", AsyncConnectionFactory, (module,))
+
+
+def instrument_aiomysql_pool(module):
+    dbapi2_module = sys.modules["aiomysql"]
+    if hasattr(module, "Pool"):
+        if hasattr(module.Pool, "_acquire"):
+            wrap_function_wrapper(module, "Pool._acquire", wrap_pool__acquire(dbapi2_module))
diff --git a/tests/datastore_aiomysql/conftest.py b/tests/datastore_aiomysql/conftest.py
new file mode 100644
index 000000000..8c8f3c5c7
--- /dev/null
+++ b/tests/datastore_aiomysql/conftest.py
@@ -0,0 +1,38 @@
+# Copyright 2010 New Relic, Inc.
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#      http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+
+from testing_support.fixture.event_loop import (  # noqa: F401; pylint: disable=W0611
+    event_loop as loop,
+)
+from testing_support.fixtures import (  # noqa: F401; pylint: disable=W0611
+    collector_agent_registration_fixture,
+    collector_available_fixture,
+)
+
+_default_settings = {
+    "package_reporting.enabled": False,  # Turn off package reporting for testing as it causes slow downs.
+    "transaction_tracer.explain_threshold": 0.0,
+    "transaction_tracer.transaction_threshold": 0.0,
+    "transaction_tracer.stack_trace_threshold": 0.0,
+    "debug.log_data_collector_payloads": True,
+    "debug.record_transaction_failure": True,
+    "debug.log_explain_plan_queries": True,
+}
+
+collector_agent_registration = collector_agent_registration_fixture(
+    app_name="Python Agent Test (datastore_aiomysql)",
+    default_settings=_default_settings,
+    linked_applications=["Python Agent Test (datastore)"],
+)
diff --git a/tests/datastore_aiomysql/test_database.py b/tests/datastore_aiomysql/test_database.py
new file mode 100644
index 000000000..b05359ac2
--- /dev/null
+++ b/tests/datastore_aiomysql/test_database.py
@@ -0,0 +1,157 @@
+# Copyright 2010 New Relic, Inc.
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#      http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+import aiomysql
+from testing_support.db_settings import mysql_settings
+from testing_support.util import instance_hostname
+from testing_support.validators.validate_database_trace_inputs import (
+    validate_database_trace_inputs,
+)
+from testing_support.validators.validate_transaction_metrics import (
+    validate_transaction_metrics,
+)
+
+from newrelic.api.background_task import background_task
+
+DB_SETTINGS = mysql_settings()[0]
+TABLE_NAME = f"datastore_aiomysql_{DB_SETTINGS['namespace']}"
+PROCEDURE_NAME = f"hello_{DB_SETTINGS['namespace']}"
+
+HOST = instance_hostname(DB_SETTINGS["host"])
+PORT = DB_SETTINGS["port"]
+
+
+async def execute_db_calls_with_cursor(cursor):
+    await cursor.execute(f"""drop table if exists {TABLE_NAME}""")
+
+    await cursor.execute(f"create table {TABLE_NAME} (a integer, b real, c text)")
+
+    await cursor.executemany(
+        f"insert into {TABLE_NAME} values (%s, %s, %s)",
+        [(1, 1.0, "1.0"), (2, 2.2, "2.2"), (3, 3.3, "3.3")],
+    )
+
+    await cursor.execute(f"""select * from {TABLE_NAME}""")
+
+    async for _ in cursor:
+        pass
+
+    await cursor.execute(f"update {TABLE_NAME} set a=%s, b=%s, c=%s where a=%s", (4, 4.0, "4.0", 1))
+
+    await cursor.execute(f"""delete from {TABLE_NAME} where a=2""")
+    await cursor.execute(f"""drop procedure if exists {PROCEDURE_NAME}""")
+    await cursor.execute(
+        f"""CREATE PROCEDURE {PROCEDURE_NAME}()
+                      BEGIN
+                        SELECT 'Hello World!';
+                      END"""
+    )
+
+    await cursor.callproc(PROCEDURE_NAME)
+
+
+SCOPED_METRICS = [
+    (f"Datastore/statement/MySQL/{TABLE_NAME}/select", 1),
+    (f"Datastore/statement/MySQL/{TABLE_NAME}/insert", 1),
+    (f"Datastore/statement/MySQL/{TABLE_NAME}/update", 1),
+    (f"Datastore/statement/MySQL/{TABLE_NAME}/delete", 1),
+    ("Datastore/operation/MySQL/drop", 2),
+    ("Datastore/operation/MySQL/create", 2),
+    (f"Datastore/statement/MySQL/{PROCEDURE_NAME}/call", 1),
+    ("Datastore/operation/MySQL/commit", 2),
+    ("Datastore/operation/MySQL/rollback", 1),
+]
+
+ROLLUP_METRICS = [
+    ("Datastore/all", 13),
+    ("Datastore/allOther", 13),
+    ("Datastore/MySQL/all", 13),
+    ("Datastore/MySQL/allOther", 13),
+    (f"Datastore/statement/MySQL/{TABLE_NAME}/select", 1),
+    (f"Datastore/statement/MySQL/{TABLE_NAME}/insert", 1),
+    (f"Datastore/statement/MySQL/{TABLE_NAME}/update", 1),
+    (f"Datastore/statement/MySQL/{TABLE_NAME}/delete", 1),
+    ("Datastore/operation/MySQL/select", 1),
+    ("Datastore/operation/MySQL/insert", 1),
+    ("Datastore/operation/MySQL/update", 1),
+    ("Datastore/operation/MySQL/delete", 1),
+    (f"Datastore/statement/MySQL/{PROCEDURE_NAME}/call", 1),
+    ("Datastore/operation/MySQL/call", 1),
+    ("Datastore/operation/MySQL/drop", 2),
+    ("Datastore/operation/MySQL/create", 2),
+    ("Datastore/operation/MySQL/commit", 2),
+    ("Datastore/operation/MySQL/rollback", 1),
+    (f"Datastore/instance/MySQL/{HOST}/{PORT}", 12),
+]
+
+
+@validate_transaction_metrics(
+    "test_database:test_execute_via_connection",
+    scoped_metrics=list(SCOPED_METRICS) + [("Function/aiomysql.connection:connect", 1)],
+    rollup_metrics=list(ROLLUP_METRICS) + [("Function/aiomysql.connection:connect", 1)],
+    background_task=True,
+)
+@validate_database_trace_inputs(sql_parameters_type=tuple)
+@background_task()
+def test_execute_via_connection(loop):
+    async def _test():
+        connection = await aiomysql.connect(
+            db=DB_SETTINGS["name"],
+            user=DB_SETTINGS["user"],
+            password=DB_SETTINGS["password"],
+            host=DB_SETTINGS["host"],
+            port=DB_SETTINGS["port"],
+        )
+
+        async with connection:
+            async with connection.cursor() as cursor:
+                await execute_db_calls_with_cursor(cursor)
+
+            await connection.commit()
+            await connection.rollback()
+            await connection.commit()
+
+    loop.run_until_complete(_test())
+
+
+@validate_transaction_metrics(
+    "test_database:test_execute_via_pool",
+    scoped_metrics=list(SCOPED_METRICS) + [("Function/aiomysql.pool:Pool._acquire", 1)],
+    rollup_metrics=list(ROLLUP_METRICS) + [("Function/aiomysql.pool:Pool._acquire", 1)],
+    background_task=True,
+)
+@validate_database_trace_inputs(sql_parameters_type=tuple)
+@background_task()
+def test_execute_via_pool(loop):
+    async def _test():
+        pool = await aiomysql.create_pool(
+            db=DB_SETTINGS["name"],
+            user=DB_SETTINGS["user"],
+            password=DB_SETTINGS["password"],
+            host=DB_SETTINGS["host"],
+            port=DB_SETTINGS["port"],
+            loop=loop,
+        )
+        async with pool.acquire() as connection:
+            async with connection.cursor() as cursor:
+                await execute_db_calls_with_cursor(cursor)
+
+            await connection.commit()
+            await connection.rollback()
+            await connection.commit()
+
+        pool.close()
+        await pool.wait_closed()
+
+    loop.run_until_complete(_test())
diff --git a/tox.ini b/tox.ini
index 6a5965ecb..81df5d404 100644
--- a/tox.ini
+++ b/tox.ini
@@ -61,6 +61,7 @@ envlist =
     mongodb8-datastore_motor-{py37,py38,py39,py310,py311,py312,py313}-motorlatest,
     mongodb3-datastore_pymongo-{py37,py38,py39,py310,py311,py312}-pymongo03,
     mongodb8-datastore_pymongo-{py37,py38,py39,py310,py311,py312,py313,pypy310}-pymongo04,
+    mysql-datastore_aiomysql-{py37,py38,py39,py310,py311,py312,py313,pypy310},
     mssql-datastore_pymssql-{py37,py38,py39,py310,py311,py312,py313},
     mysql-datastore_mysql-mysqllatest-{py37,py38,py39,py310,py311,py312,py313},
     mysql-datastore_pymysql-{py37,py38,py39,py310,py311,py312,py313,pypy310},
@@ -251,6 +252,8 @@ deps =
     cross_agent: requests
     datastore_asyncpg: asyncpg
     datastore_aiomcache: aiomcache
+    datastore_aiomysql: aiomysql
+    datastore_aiomysql: cryptography
     datastore_bmemcached: python-binary-memcached
     datastore_elasticsearch: requests
     datastore_elasticsearch-elasticsearch07: elasticsearch<8.0
@@ -466,9 +469,10 @@ changedir =
     component_tastypie: tests/component_tastypie
     coroutines_asyncio: tests/coroutines_asyncio
     cross_agent: tests/cross_agent
+    datastore_aiomcache: tests/datastore_aiomcache
+    datastore_aiomysql: tests/datastore_aiomysql
     datastore_asyncpg: tests/datastore_asyncpg
     datastore_bmemcached: tests/datastore_bmemcached
-    datastore_aiomcache: tests/datastore_aiomcache
     datastore_elasticsearch: tests/datastore_elasticsearch
     datastore_firestore: tests/datastore_firestore
     datastore_memcache: tests/datastore_memcache