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[Text and logical def] tuft cell of colon #2949

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Caroline-99 opened this issue Feb 11, 2025 · 0 comments
Open

[Text and logical def] tuft cell of colon #2949

Caroline-99 opened this issue Feb 11, 2025 · 0 comments
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CL term
tuft cell of colon

Suggested revision of textual definition

A tuft cell that is part of the colonic epithelium, specialized in microbial sensing within the dense colonic microbiota. Unlike small intestinal tuft cells, it plays a minimal role in type 2 immunity, instead detecting bacterial metabolites via taste signalling pathways. This cell also serves as a reserve stem cell, capable of regenerating other epithelial cell types during injury or stress.

PMID:39358509
PMID:35271673
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