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Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)
A tuft cell that is part of the epithelium of urethra. This cell monitors urethral contents by detecting chemical stimuli, such as bitter compounds and sugars. Upon activation, it releases acetylcholine (ACh), stimulating sensory nerve fibres and triggering detrusor muscle contraction, likely aiding in pathogen clearance by promoting bladder emptying.
Fixes#2959
- NTR tuft cell of urethra
- Links to GO term - 'capable of' some 'positive regulation of smooth muscle contraction involved in micturition'
Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl
Preferred term label
tuft cell of urethra
Synonyms (add reference(s), please)
urethral tuft cell - exact synonym - PMID: 38548667
urethral brush cell - exact synonym - PMID: 38548667
urethral cholinergic chemosensory cell - exact synonym - PMID: 38548667
Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)
A tuft cell that is part of the epithelium of urethra. This cell monitors urethral contents by detecting chemical stimuli, such as bitter compounds and sugars. Upon activation, it releases acetylcholine (ACh), stimulating sensory nerve fibres and triggering detrusor muscle contraction, likely aiding in pathogen clearance by promoting bladder emptying.
PMID: 30379593
PMID: 38548667
PMID: 36993541
Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
brush cell
Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
epithelium of urethra
Your ORCID
Additional notes or concerns
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