Ensure Python (>= 2.7) is installed.
Install Pandoc from http://johnmacfarlane.net/pandoc/installing.html
Install pdflatex from http://www.tug.org/texlive/.
Note that Mac users can install MacTex.pkg from http://www.tug.org/mactex/2012/.
Install pip if not present already:
sudo sh -c "curl -k -O https://raw.github.com/pypa/pip/master/contrib/get-pip.py && python get-pip.py && rm get-pip.py"
Install Python libraries needed:
sudo pip install -r requirements.txt
Convert the source files into HTML files:
fab html
Convert the source files into PDF:
fab pdf
Convert the source files into EPUB (ebook):
fab epub
If you're using Vim editor, then you may like the vim-pandoc plugin. There is one downside though - for long chapters, it becomes really slow, so I edit only in plain text mode (:set ft=), but when reviewing, I use the pandoc (:set ft=pandoc) mode.